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Other systemic involvement of connective tissue

DOIDEFOMESHSNOMED PheWeb

M13_OTHCONN

connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M35
Cause of death: ICD-10 M35

6607

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

6607

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Check minimum number of events None

6607

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Include endpoints

6943

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M13_OTHCONN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30-M36
Name in latin Aliae morbositates systemicae textus connectivi

Similar endpoints

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List of similar endpoints to Other systemic involvement of connective tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 6753 5071 1682
Unadjusted prevalence (%) 2.19 2.92 1.25
Mean age at first event (years) 55.70 53.39 62.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.47 [1.71, 3.56] 1.3e-6 665
15 years 0.01 1.34 [1.03, 1.75] 3.1e-2 280
5 years 0.00 2.81 [2.29, 3.44] 1.9e-23 213
1 year 0.00 6.28 [4.90, 8.05] 2.0e-47 102

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_OTHCONN – Other systemic involvement of connective tissue
GWS hits: 4

Survival analyses between endpoints

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Plot

before Other systemic involvement of connective tissue
after Other systemic involvement of connective tissue

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Drugs most likely to be purchased after Other systemic involvement of connective tissue

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