Other systemic involvement of connective tissue (FG)

OTHER_SYSTCON_FG

connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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OTHER_SYSTCON_FG

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Other systemic involvement of connective tissue (FG) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 6614 4995 1619
Unadjusted prevalence (%) 2.14 2.88 1.20
Mean age at first event (years) 55.86 53.46 63.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.76 [2.25, 3.39] 3.7e-22 645
15 years 0.01 1.40 [1.13, 1.73] 2.2e-3 277
5 years 0.00 2.67 [2.19, 3.27] 1.2e-21 203
1 year 0.00 5.84 [4.54, 7.53] 1.9e-42 95

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: OTHER_SYSTCON_FG – Other systemic involvement of connective tissue (FG)
GWS hits: 5

Survival analyses between endpoints

Plot

before Other systemic involvement of connective tissue (FG)
after Other systemic involvement of connective tissue (FG)

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Drugs most likely to be purchased after Other systemic involvement of connective tissue (FG)