Polymyalgia rheumatica

M13_POLYMYALGIA

polymyalgia rheumatica: Polymyalgia rheumatica is a common inflammatory condition that often affects people over the age of 50 years. Characteristic symptoms are shoulder and hip girdle pain and prolonged morning stiffness. Markers of inflammation are often elevated.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M35.3

Hospital discharge: ICD-9 725

Hospital discharge: ICD-8 4463

Cause of death: ICD-10 M35.3

Cause of death: ICD-9 725

Cause of death: ICD-8 4463

5232

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2607

Check minimum number of events None

2607

Include endpoints None

2607

M13_POLYMYALGIA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M35

Name in latin Polymyalgia rheumatica

Similar endpoints

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List of similar endpoints to Polymyalgia rheumatica based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2535	1515	1020
Unadjusted prevalence (%)	0.82	0.87	0.76
Mean age at first event (years)	69.18	68.73	69.86

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.97 [1.27, 3.05]	2.5e-3	443
15 years	0.01	0.93 [0.66, 1.31]	6.7e-1	168
5 years	0.00	2.57 [2.00, 3.29]	1.0e-13	165
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLYMYALGIA – Polymyalgia rheumatica
GWS hits: 2

Survival analyses between endpoints

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Plot

before Polymyalgia rheumatica
after Polymyalgia rheumatica

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Table

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Drugs most likely to be purchased after Polymyalgia rheumatica

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