Polymyalgia rheumatica


polymyalgia rheumatica: Polymyalgia rheumatica is a common inflammatory condition that often affects people over the age of 50 years. Characteristic symptoms are shoulder and hip girdle pain and prolonged morning stiffness. Markers of inflammation are often elevated.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M35.3
Hospital discharge: ICD-9 725
Hospital discharge: ICD-8 4463
Cause of death: ICD-10 M35.3
Cause of death: ICD-9 725
Cause of death: ICD-8 4463


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M35
Name in latin Polymyalgia rheumatica

Summary Statistics

Key figures

All Female Male
Number of individuals 2535 1515 1020
Unadjusted prevalence (%) 0.82 0.87 0.76
Mean age at first event (years) 69.18 68.73 69.86


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.97 [1.27, 3.05] 2.5e-3 443
15 years 0.01 0.93 [0.66, 1.31] 6.7e-1 168
5 years 0.00 2.57 [2.00, 3.29] 1.0e-13 165
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_POLYMYALGIA – Polymyalgia rheumatica
GWS hits: 2

Survival analyses between endpoints


before Polymyalgia rheumatica
after Polymyalgia rheumatica

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Drugs most likely to be purchased after Polymyalgia rheumatica