Multifocal fibrosclerosis

M13_MULTIFIBRO

multiple sclerosis: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M35.5

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M35.5

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

140

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

140

Check minimum number of events None

140

Include endpoints None

140

M13_MULTIFIBRO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M35

Name in latin Fibrosclerosis multifocalis

Similar endpoints

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List of similar endpoints to Multifocal fibrosclerosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	137	99	38
Unadjusted prevalence (%)	0.04	0.06	0.03
Mean age at first event (years)	60.30	59.22	63.12

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MULTIFIBRO – Multifocal fibrosclerosis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Multifocal fibrosclerosis
after Multifocal fibrosclerosis

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Table

Loading survival analyses table

Drugs most likely to be purchased after Multifocal fibrosclerosis

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