COPD-associated co-morbidities

PheWeb

COPD_COMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

K11_REFLUX

E4_OBESITY

R18_MOUTH_BREAT

VOCALCORDDYS

COPD_CVDMETABOCOMORB

PULM_IMMUNECOMORB

SMOKING

TRACHEOBRONCHOMAL

ABPA

D3_IMMUDEF

PULM_PSYCH_COMORB

182009

COPD_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to COPD-associated co-morbidities based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	175909	90657	85252
Unadjusted prevalence (%)	57.01	52.24	63.14
Mean age at first event (years)	49.49	47.36	51.75

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	5.13 [4.78, 5.50]	<1e-100	22475
15 years	0.01	3.52 [3.25, 3.81]	<1e-100	10423
5 years	0.00	4.94 [4.49, 5.43]	<1e-100	4376
1 year	0.00	20.60 [17.39, 24.40]	<1e-100	3222

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: COPD_COMORB – COPD-associated co-morbidities
GWS hits:

Survival analyses between endpoints

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Plot

before COPD-associated co-morbidities
after COPD-associated co-morbidities

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after COPD-associated co-morbidities

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