Diabetes mellitus

E4_DIABETES

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

↥
FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector

Filter registries None

0

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

55495

diagram downward connector
E4_DIABETES

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF3

Similar endpoints

↥

List of similar endpoints to Diabetes mellitus based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 53688 24415 29273
Unadjusted prevalence (%) 17.40 14.07 21.68
Mean age at first event (years) 54.51 52.77 55.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.65 [2.42, 2.91] 6.3e-95 8081
15 years 0.01 1.80 [1.66, 1.95] 9.1e-45 4070
5 years 0.00 2.69 [2.48, 2.90] <1e-100 1974
1 year 0.00 4.72 [4.16, 5.35] <1e-100 683

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_DIABETES – Diabetes mellitus
GWS hits: 103

Survival analyses between endpoints

↥

Plot

before Diabetes mellitus
after Diabetes mellitus

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetes mellitus

↥