Type 2 diabetes


type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E11
Cause of death: ICD-10 E11
Medicine purchases: ATC A10B


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


diagram downward connector
diagram bullet

Check minimum number of events

Min. number of events 3


diagram downward connector

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) [obesus/non obesus] adultorum

Similar endpoints

List of similar endpoints to Type 2 diabetes based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 49303 22142 27161
Unadjusted prevalence (%) 15.98 12.76 20.12
Mean age at first event (years) 58.72 57.62 59.61


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.46 [2.22, 2.72] 2.1e-69 7830
15 years 0.01 1.69 [1.54, 1.85] 1.5e-29 3995
5 years 0.00 2.64 [2.43, 2.87] <1e-100 1958
1 year 0.00 4.64 [4.09, 5.27] <1e-100 668

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_DM2 – Type 2 diabetes
GWS hits: 105

Survival analyses between endpoints


before Type 2 diabetes
after Type 2 diabetes

loading spinner Loading survival analyses plot