Biguanides

BIGUANIDES

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Medicine purchases: ATC A10BA

44761

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Check pre-conditions, main-only, mode, ICD version None

40267

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Check minimum number of events

Min. number of events 3

40267

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Include endpoints None

40267

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BIGUANIDES

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 38943 17573 21370
Unadjusted prevalence (%) 12.62 10.13 15.83
Mean age at first event (years) 59.47 58.29 60.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.03 [1.82, 2.27] 6.8e-36 5076
15 years 0.01 1.50 [1.36, 1.65] 4.7e-16 2882
5 years 0.00 2.18 [1.99, 2.39] 1.3e-61 1275
1 year 0.00 1.61 [1.34, 1.92] 2.4e-7 174

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: BIGUANIDES – Biguanides
GWS hits:

Survival analyses between endpoints

Plot

before Biguanides
after Biguanides

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