Biguanides

PheWeb

BIGUANIDES

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC A10BA

44761

Check pre-conditions, main-only, mode, ICD version None

40267

Check minimum number of events

Min. number of events 3

40267

Include endpoints None

40267

BIGUANIDES

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Biguanides based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	38943	17573	21370
Unadjusted prevalence (%)	12.62	10.13	15.83
Mean age at first event (years)	59.47	58.29	60.44

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.03 [1.82, 2.27]	6.8e-36	5076
15 years	0.01	1.50 [1.36, 1.65]	4.7e-16	2882
5 years	0.00	2.18 [1.99, 2.39]	1.3e-61	1275
1 year	0.00	1.61 [1.34, 1.92]	2.4e-7	174

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: BIGUANIDES – Biguanides
GWS hits:

Survival analyses between endpoints

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Plot

before Biguanides
after Biguanides

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Biguanides

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