Co-morbidites, CVD and metabolic diseases

PheWeb

ASTHMA_CVDMETABOCOMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_ISCHHEART

I9_CEREBVASC

I9_SECONDRIGHT

I9_PAROXTAC

I9_AF

E4_DIABETES

115115

ASTHMA_CVDMETABOCOMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Co-morbidites, CVD and metabolic diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	111507	48517	62990
Unadjusted prevalence (%)	36.14	27.96	46.65
Mean age at first event (years)	57.55	56.76	58.16

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	4.66 [4.35, 4.98]	<1e-100	20295
15 years	0.01	3.05 [2.83, 3.29]	<1e-100	9170
5 years	0.00	4.69 [4.30, 5.11]	<1e-100	4272
1 year	0.00	21.15 [18.25, 24.51]	<1e-100	3593

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_CVDMETABOCOMORB – Co-morbidites, CVD and metabolic diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Co-morbidites, CVD and metabolic diseases
after Co-morbidites, CVD and metabolic diseases

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Table

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Drugs most likely to be purchased after Co-morbidites, CVD and metabolic diseases

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