ILD-related co-morbidities

PheWeb

ILD_COMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

RESPIRATORYINSUFF

CPAP

NIV

K11_REFLUX

E4_OBESITY

TRACHEOBRONCHOMAL

D3_IMMUDEF

ILD_CVDMETABOCOMORB

PULM_PSYCH_COMORB

SMOKING

170970

ILD_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to ILD-related co-morbidities based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	165201	83612	81589
Unadjusted prevalence (%)	53.54	48.18	60.43
Mean age at first event (years)	50.89	48.76	53.06

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	5.79 [5.41, 6.19]	<1e-100	22488
15 years	0.01	3.82 [3.53, 4.12]	<1e-100	10257
5 years	0.00	5.35 [4.88, 5.87]	<1e-100	4483
1 year	0.00	23.57 [19.95, 27.84]	<1e-100	3617

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ILD_COMORB – ILD-related co-morbidities
GWS hits:

Survival analyses between endpoints

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Plot

before ILD-related co-morbidities
after ILD-related co-morbidities

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after ILD-related co-morbidities

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