Obesity

E4_OBESITY

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E66
Cause of death: ICD-10 E66

15353

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

15353

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Check minimum number of events None

15353

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E4_OBESITY

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E65-E68
Name in latin Obesitas

Similar endpoints

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List of similar endpoints to Obesity based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 15517 10105 5412
Unadjusted prevalence (%) 5.03 5.82 4.01
Mean age at first event (years) 49.04 46.80 53.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.92 [3.07, 4.99] 2.1e-28 1125
15 years 0.01 2.20 [1.79, 2.70] 6.4e-14 466
5 years 0.00 4.53 [3.79, 5.42] 3.4e-62 311
1 year 0.00 16.41 [13.45, 20.02] <1e-100 222

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITY – Obesity
GWS hits: 11

Survival analyses between endpoints

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Plot

before Obesity
after Obesity

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