Obesity

E4_OBESITY

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E66
Cause of death: ICD-10 E66

15353

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

15353

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Check minimum number of events None

15353

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E4_OBESITY

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E65-E68
Name in latin Obesitas

Similar endpoints

List of similar endpoints to Obesity based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 15517 10105 5412
Unadjusted prevalence (%) 5.03 5.82 4.01
Mean age at first event (years) 49.04 46.80 53.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.92 [3.07, 4.99] 2.1e-28 1125
15 years 0.01 2.20 [1.79, 2.70] 6.4e-14 466
5 years 0.00 4.53 [3.79, 5.42] 3.4e-62 311
1 year 0.00 16.41 [13.45, 20.02] <1e-100 222

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_OBESITY – Obesity
GWS hits: 11

Survival analyses between endpoints

Plot

before Obesity
after Obesity

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