Endocrine, nutritional and metabolic diseases

PheWeb

E4_ENDONUTRMET

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E00-E90

Cause of death: ICD-10 E00-E90

101163

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

89388

Check minimum number of events None

89388

Include endpoints

E4_THYROID

E4_DIABETES

E4_GLUCOPANCREAS

E4_ENDOGLAND

E4_MALNUTRITION

E4_NUTRIDEF

E4_OBESITY

E4_METABOLIA

122602

E4_ENDONUTRMET

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Endocrine, nutritional and metabolic diseases based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	118526	68817	49709
Unadjusted prevalence (%)	38.41	39.66	36.82
Mean age at first event (years)	52.60	49.96	56.26

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.62 [2.42, 2.83]	<1e-100	13559
15 years	0.01	1.72 [1.59, 1.85]	2.2e-47	6492
5 years	0.00	2.68 [2.50, 2.88]	<1e-100	3321
1 year	0.00	6.46 [5.77, 7.23]	<1e-100	1598

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDONUTRMET – Endocrine, nutritional and metabolic diseases
GWS hits: 31

Survival analyses between endpoints

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Plot

before Endocrine, nutritional and metabolic diseases
after Endocrine, nutritional and metabolic diseases

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Table

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Drugs most likely to be purchased after Endocrine, nutritional and metabolic diseases

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