Other disorders of glucose regulation and pancreatic internal secretion

DOID MESH PheWeb

E4_GLUCOPANCREAS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E15-E16

Cause of death: ICD-10 E15-E16

1741

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1741

Check minimum number of events None

1741

Include endpoints

E4_HYPOCOMA

E4_HYPODRUG

E4_HYPOGLYC

E4_GLUCAGONPLUS

E4_ABNGASTRIN

E4_PANCSECNAS

2037

E4_GLUCOPANCREAS

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other disorders of glucose regulation and pancreatic internal secretion based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

1989

950

1039

Unadjusted prevalence (%)

0.64

0.55

0.77

Mean age at first event (years)

46.23

42.66

49.49

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	7.24 [4.82, 10.85]	1.1e-21	406
15 years	0.01	2.42 [1.58, 3.70]	4.9e-5	120
5 years	0.01	6.38 [4.20, 9.70]	4.4e-18	158
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GLUCOPANCREAS – Other disorders of glucose regulation and pancreatic internal secretion
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other disorders of glucose regulation and pancreatic internal secretion
after Other disorders of glucose regulation and pancreatic internal secretion

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Table

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Drugs most likely to be purchased after Other disorders of glucose regulation and pancreatic internal secretion

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