Endocrine, nutritional and metabolic diseases

PheWeb

IV_ENDOCRIN_NUTRIT

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E00-E90

Hospital discharge: ICD-9 2[4-7]

Hospital discharge: ICD-8 2[4-7]

Cause of death: ICD-10 E00-E90

Cause of death: ICD-9 2[4-7]

Cause of death: ICD-8 2[4-7]

105026

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

93573

Check minimum number of events None

93573

Include endpoints None

93573

IV_ENDOCRIN_NUTRIT

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Endocrine, nutritional and metabolic diseases based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	90460	50586	39874
Unadjusted prevalence (%)	29.32	29.15	29.53
Mean age at first event (years)	53.41	50.69	56.87

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.46 [3.20, 3.75]	<1e-100	11988
15 years	0.01	2.00 [1.84, 2.16]	7.2e-63	4926
5 years	0.00	3.65 [3.39, 3.93]	<1e-100	3359
1 year	0.00	11.84 [10.63, 13.20]	<1e-100	2364

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: IV_ENDOCRIN_NUTRIT – Endocrine, nutritional and metabolic diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Endocrine, nutritional and metabolic diseases
after Endocrine, nutritional and metabolic diseases

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Table

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Drugs most likely to be purchased after Endocrine, nutritional and metabolic diseases

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