Pure hypercholesterolaemia

DOID MESH PheWeb

E4_HYPERCHOL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E78.0

Hospital discharge: ICD-9 2720

Hospital discharge: ICD-8 2720

Cause of death: ICD-10 E78.0

Cause of death: ICD-9 2720

Cause of death: ICD-8 2720

19915

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

19915

Check minimum number of events None

19915

Include endpoints

E4_FH

19915

E4_HYPERCHOL

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E78

Name in latin Hypercholesterolaemia pura

Similar endpoints

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List of similar endpoints to Pure hypercholesterolaemia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	19284	8517	10767
Unadjusted prevalence (%)	6.25	4.91	7.97
Mean age at first event (years)	65.06	65.47	64.73

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.68 [2.16, 3.32]	4.1e-19	2215
15 years	0.01	1.21 [1.00, 1.47]	4.8e-2	828
5 years	0.00	3.13 [2.72, 3.60]	9.0e-57	805
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPERCHOL – Pure hypercholesterolaemia
GWS hits: 21

Survival analyses between endpoints

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Plot

before Pure hypercholesterolaemia
after Pure hypercholesterolaemia

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Table

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Drugs most likely to be purchased after Pure hypercholesterolaemia

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