Disorders of lipoprotein metabolism and other lipidaemias

DOID MESH PheWeb

E4_LIPOPROT

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E78

Cause of death: ICD-10 E78

29220

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

29220

Check minimum number of events None

29220

Include endpoints

E4_HYPERCHOL

E4_HYPERGLYCER

E4_HYPERLIPMIX

E4_HYPERCHYLO

E4_HYPERLIPNAS

E4_LIPODEF

E4_LIPOPROTNAS

29455

E4_LIPOPROT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E70-E90

Name in latin Perturbationes metabolismi lipoproteinorum et aliae lipidaemiae

Similar endpoints

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List of similar endpoints to Disorders of lipoprotein metabolism and other lipidaemias based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	28524	12470	16054
Unadjusted prevalence (%)	9.24	7.19	11.89
Mean age at first event (years)	64.27	64.84	63.83

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.85 [2.51, 3.23]	1.8e-58	3398
15 years	0.01	1.42 [1.25, 1.61]	7.3e-8	1446
5 years	0.00	2.88 [2.58, 3.21]	2.4e-78	1162
1 year	0.00	8.01 [6.99, 9.19]	<1e-100	639

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_LIPOPROT – Disorders of lipoprotein metabolism and other lipidaemias
GWS hits: 30

Survival analyses between endpoints

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Plot

before Disorders of lipoprotein metabolism and other lipidaemias
after Disorders of lipoprotein metabolism and other lipidaemias

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Table

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Drugs most likely to be purchased after Disorders of lipoprotein metabolism and other lipidaemias

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