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Type 2 diabetes without complications

DOIDEFOMESHSNOMED PheWeb

E4_DM2NOCOMP

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E11.9
Hospital discharge: ICD-9 2500A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E11.9
Cause of death: ICD-9 2500A
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

25701

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E4_DM2NOCOMP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E11

Summary Statistics

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Key figures

All Female Male
Number of individuals 24905 10424 14481
Unadjusted prevalence (%) 8.07 6.01 10.72
Mean age at first event (years) 62.81 62.08 63.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.01 [3.52, 4.55] 8.3e-100 5860
15 years 0.01 2.16 [1.93, 2.42] 3.1e-40 2336
5 years 0.00 4.06 [3.70, 4.46] <1e-100 1792
1 year 0.00 13.47 [11.97, 15.16] <1e-100 1306

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM2NOCOMP – Type 2 diabetes without complications
GWS hits: 41

Survival analyses between endpoints

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Plot

before Type 2 diabetes without complications
after Type 2 diabetes without complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 2 diabetes without complications

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