Disorders of other endocrine glands

DOID EFO MESH SNOMED PheWeb

E4_ENDOGLAND

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E20-E35

Cause of death: ICD-10 E20-E35

8923

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8898

Check minimum number of events None

8898

Include endpoints

E4_PARATHYRO

E4_HYPERPIT

E4_HYPOPIT

E4_DIABINSIPIDUS

E4_HYPOTHALDYSF

E4_PITUDISNAS

E4_CUSHING

E4_ADRENOGEN

E4_HYPERALDO

E4_ADRENAL

E4_OVARDYS

E4_TESTIDYS

E4_DISPUB

E4_DYSPOLYGL

E4_THYMUSDIS

E4_ENDODIS

11999

E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of other endocrine glands based on the number of shared cases.

Broader endpoints:

Endocrine, nutritional and metabolic diseases

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	11564	7929	3635
Unadjusted prevalence (%)	3.75	4.57	2.69
Mean age at first event (years)	48.85	47.79	51.16

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.14 [1.65, 2.78]	9.3e-9	1318
15 years	0.01	1.37 [1.11, 1.69]	3.2e-3	606
5 years	0.00	2.71 [2.31, 3.18]	4.5e-34	385
1 year	0.00	5.90 [4.80, 7.25]	9.3e-64	165

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDOGLAND – Disorders of other endocrine glands
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders of other endocrine glands
after Disorders of other endocrine glands

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Table

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Drugs most likely to be purchased after Disorders of other endocrine glands

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