Hyperaldosteronism

E4_HYPERALDO

hyperaldosteronism: Overproduction of aldosterone by the adrenal glands, which may lead to hypokalemia and/or hypernatremia. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E26

Hospital discharge: ICD-9 2551

Hospital discharge: ICD-8 25500

Cause of death: ICD-10 E26

Cause of death: ICD-9 2551

Cause of death: ICD-8 25500

570

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

540

Check minimum number of events None

540

Include endpoints None

540

E4_HYPERALDO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E20-E35

Name in latin Hyperaldosteronismus

Similar endpoints

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List of similar endpoints to Hyperaldosteronism based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	522	290	232
Unadjusted prevalence (%)	0.17	0.17	0.17
Mean age at first event (years)	56.17	54.15	58.69

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.77 [1.51, 5.07]	9.5e-4	36
15 years	0.01	1.80 [1.00, 3.22]	4.9e-2	19
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPERALDO – Hyperaldosteronism
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hyperaldosteronism
after Hyperaldosteronism

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Table

Loading survival analyses table

Drugs most likely to be purchased after Hyperaldosteronism

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