Disorders of puberty

DOID MESH PheWeb

E4_DISPUB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E30

Cause of death: ICD-10 E30

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

Check minimum number of events None

Include endpoints

E4_DELPUB

E4_PREPUB

E4_PUBDISNAS

351

E4_DISPUB

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E20-E35

Name in latin Perturbationes pubertatis non alibi classificatae

Similar endpoints

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List of similar endpoints to Disorders of puberty based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

329

205

124

Unadjusted prevalence (%)

0.11

0.12

0.09

Mean age at first event (years)

16.16

15.46

17.33

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	7.66 [1.88, 31.22]	4.5e-3	10
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DISPUB – Disorders of puberty
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of puberty
after Disorders of puberty

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Table

Loading survival analyses table

Drugs most likely to be purchased after Disorders of puberty

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