Disorders of puberty


No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 E30
Cause of death: ICD-10 E30


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Include endpoints


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Perturbationes pubertatis non alibi classificatae

Summary Statistics

Key figures

All Female Male
Number of individuals 329 205 124
Unadjusted prevalence (%) 0.11 0.12 0.09
Mean age at first event (years) 16.16 15.46 17.33


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 7.66 [1.88, 31.22] 4.5e-3 10
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_DISPUB – Disorders of puberty
GWS hits: 0

Survival analyses between endpoints


before Disorders of puberty
after Disorders of puberty

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Drugs most likely to be purchased after Disorders of puberty