Obesity due to excess calories

DOID EFO MESH SNOMED PheWeb

E4_OBESITYCAL

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E66.00, E66.01

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E66.00, E66.01

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

11167

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

11167

Check minimum number of events None

11167

Include endpoints None

11167

E4_OBESITYCAL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Obesity due to excess calories based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	10780	6964	3816
Unadjusted prevalence (%)	3.49	4.01	2.83
Mean age at first event (years)	50.16	47.62	54.79

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.56 [2.65, 4.79]	3.4e-17	647
15 years	0.01	1.96 [1.50, 2.55]	6.6e-7	275
5 years	0.01	4.84 [3.84, 6.11]	2.8e-40	207
1 year	0.00	15.19 [11.74, 19.64]	2.7e-95	124

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYCAL – Obesity due to excess calories
GWS hits: 8

Survival analyses between endpoints

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Plot

before Obesity due to excess calories
after Obesity due to excess calories

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Table

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Drugs most likely to be purchased after Obesity due to excess calories

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