Obesity, other/unspecified

DOID EFO MESH SNOMED PheWeb

E4_OBESITYNAS

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E66.8, E66.9

Hospital discharge: ICD-9 2780

Hospital discharge: ICD-8 27799

Cause of death: ICD-10 E66.8, E66.9

Cause of death: ICD-9 2780

Cause of death: ICD-8 27799

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

8390

E4_OBESITYNAS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Obesity, other/unspecified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8129	5513	2616
Unadjusted prevalence (%)	2.63	3.18	1.94
Mean age at first event (years)	47.52	45.81	51.11

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.67 [1.83, 3.90]	3.6e-7	663
15 years	0.01	1.48 [1.07, 2.03]	1.7e-2	259
5 years	0.00	3.65 [2.80, 4.77]	1.1e-21	178
1 year	0.00	14.66 [11.12, 19.34]	1.3e-80	136

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYNAS – Obesity, other/unspecified
GWS hits: 6

Survival analyses between endpoints

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Plot

before Obesity, other/unspecified
after Obesity, other/unspecified

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Table

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Drugs most likely to be purchased after Obesity, other/unspecified

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