Extreme obesity with alveolar hypoventilation

DOID EFO MESH SNOMED PheWeb

E4_OBESITYXTRMALV

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E66.2

Hospital discharge: ICD-9 2788A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E66.2

Cause of death: ICD-9 2788A

Cause of death: ICD-8 $!$

791

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

791

Check minimum number of events None

791

Include endpoints None

791

E4_OBESITYXTRMALV

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E66

Name in latin Obesitas extrema cum hypoventilatione alveolari

Similar endpoints

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List of similar endpoints to Extreme obesity with alveolar hypoventilation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	777	440	337
Unadjusted prevalence (%)	0.25	0.25	0.25
Mean age at first event (years)	58.14	56.57	60.20

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.16	13.61 [7.20, 25.73]	9.2e-16	124
15 years	0.02	3.04 [1.51, 6.13]	1.8e-3	26
5 years	0.02	14.41 [7.60, 27.31]	2.9e-16	53
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYXTRMALV – Extreme obesity with alveolar hypoventilation
GWS hits: 1

Survival analyses between endpoints

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Plot

before Extreme obesity with alveolar hypoventilation
after Extreme obesity with alveolar hypoventilation

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Table

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Drugs most likely to be purchased after Extreme obesity with alveolar hypoventilation

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