Cerebrovascular diseases

I9_CEREBVASC

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I60-I69
Cause of death: ICD-10 I60-I69

24441

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

24441

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Check minimum number of events None

24441

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I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Cerebrovascular diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 24990 10277 14713
Unadjusted prevalence (%) 8.10 5.92 10.90
Mean age at first event (years) 65.12 64.10 65.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.93 [3.46, 4.47] 2.8e-98 7469
15 years 0.01 1.78 [1.58, 2.01] 9.0e-21 2507
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CEREBVASC – Cerebrovascular diseases
GWS hits: 1

Survival analyses between endpoints

Plot

before Cerebrovascular diseases
after Cerebrovascular diseases

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Drugs most likely to be purchased after Cerebrovascular diseases