Ischaemic Stroke, excluding all haemorrhages

I9_STR_EXH

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I63, I64

Hospital discharge: ICD-9 4330A|4331A|4339A|4340A|4341A|4349A|436

Hospital discharge: ICD-8 433|434|436

Hospital discharge: excluded ICD-10 I63.6

Cause of death: ICD-10 I63, I64

Cause of death: ICD-9 4330A|4331A|4339A|4340A|4341A|4349A|436

Cause of death: ICD-8 433|434|436

Cause of death: excluded ICD-10 I63.6

17536

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

17448

Check minimum number of events None

17448

Include endpoints

I9_STR_EMBOLIC

17448

I9_STR_EXH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

↥

List of similar endpoints to Ischaemic Stroke, excluding all haemorrhages based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	16857	6600	10257
Unadjusted prevalence (%)	5.46	3.80	7.60
Mean age at first event (years)	66.54	66.35	66.66

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.43 [3.92, 5.01]	<1e-100	5440
15 years	0.01	1.99 [1.78, 2.23]	4.4e-32	1867
5 years	0.00	4.25 [3.86, 4.67]	<1e-100	1620
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: I9_STR_EXH – Ischaemic Stroke, excluding all haemorrhages
GWS hits: 2

Survival analyses between endpoints

↥

Plot

before Ischaemic Stroke, excluding all haemorrhages
after Ischaemic Stroke, excluding all haemorrhages

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Ischaemic Stroke, excluding all haemorrhages

↥