Stroke, including SAH

I9_STR_SAH

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I60, I61, I63, I64

Hospital discharge: ICD-9 430|431|4330A|4331A|4339A|4340A|4341A|4349A|436

Hospital discharge: ICD-8 430|431|433|434|436

Hospital discharge: excluded ICD-10 I63.6

Hospital discharge: excluded ICD-8 43101|43191

Cause of death: ICD-10 I60, I61, I63, I64

Cause of death: ICD-9 430|431|4330A|4331A|4339A|4340A|4341A|4349A|436

Cause of death: ICD-8 430|431|433|434|436

Cause of death: excluded ICD-10 I63.6

Cause of death: excluded ICD-8 43101|43191

20816

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

20729

Check minimum number of events None

20729

Include endpoints None

20729

I9_STR_SAH

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Stroke, including SAH based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	20029	7992	12037
Unadjusted prevalence (%)	6.49	4.61	8.91
Mean age at first event (years)	65.44	64.92	65.78

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.68 [4.14, 5.29]	<1e-100	6483
15 years	0.01	2.06 [1.84, 2.30]	6.9e-37	2078
5 years	0.00	4.45 [4.05, 4.88]	<1e-100	1771
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_STR_SAH – Stroke, including SAH
GWS hits: 1

Survival analyses between endpoints

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Plot

before Stroke, including SAH
after Stroke, including SAH

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Table

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Drugs most likely to be purchased after Stroke, including SAH

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