Rheumatoid arthritis -related co-morbidities

PheWeb

RA_CO_MORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_ISCHHEART

C_STROKE

C_LYMPHOMA

E4_AMYLOIDOSIS

LUNG_CANCER_MESOT

72266

RA_CO_MORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Rheumatoid arthritis -related co-morbidities based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	70007	26905	43102
Unadjusted prevalence (%)	22.69	15.50	31.92
Mean age at first event (years)	63.18	63.46	63.00

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	6.16 [5.72, 6.64]	<1e-100	18520
15 years	0.02	3.62 [3.33, 3.94]	<1e-100	7020
5 years	0.01	6.88 [6.30, 7.51]	<1e-100	4118
1 year	0.01	45.46 [39.04, 52.93]	<1e-100	5314

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RA_CO_MORB – Rheumatoid arthritis -related co-morbidities
GWS hits:

Survival analyses between endpoints

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Plot

before Rheumatoid arthritis -related co-morbidities
after Rheumatoid arthritis -related co-morbidities

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Table

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Drugs most likely to be purchased after Rheumatoid arthritis -related co-morbidities

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