Lung cancer and mesothelioma

LUNG_CANCER_MESOT

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 C34, C38.4&
Hospital discharge: ICD-9 162|163
Hospital discharge: ICD-8 162|16301
Cause of death: ICD-10 C34, C38.4&
Cause of death: ICD-9 162|163
Cause of death: ICD-8 162|16301
Cancer registry: Topography ICD-O-3 C34|C384

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

5328

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LUNG_CANCER_MESOT

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Lung cancer and mesothelioma based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 5157 1331 3826
Unadjusted prevalence (%) 1.67 0.77 2.83
Mean age at first event (years) 69.95 66.81 71.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.28 25.84 [21.58, 30.94] <1e-100 2732
15 years 0.01 2.20 [1.78, 2.71] 1.9e-13 166
5 years 0.02 16.90 [14.41, 19.81] <1e-100 731
1 year 0.02 91.86 [80.17, 105.27] <1e-100 1826

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: LUNG_CANCER_MESOT – Lung cancer and mesothelioma
GWS hits:

Survival analyses between endpoints

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Plot

before Lung cancer and mesothelioma
after Lung cancer and mesothelioma

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Drugs most likely to be purchased after Lung cancer and mesothelioma

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