Lung cancer and mesothelioma

LUNG_CANCER_MESOT

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 C34, C38.4&
Hospital discharge: ICD-9 162|163
Hospital discharge: ICD-8 162|16301
Cause of death: ICD-10 C34, C38.4&
Cause of death: ICD-9 162|163
Cause of death: ICD-8 162|16301
Cancer registry: Topography ICD-O-3 C34|C384

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

5328

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LUNG_CANCER_MESOT

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Lung cancer and mesothelioma based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5157 1331 3826
Unadjusted prevalence (%) 1.67 0.77 2.83
Mean age at first event (years) 69.95 66.81 71.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.28 25.84 [21.58, 30.94] <1e-100 2732
15 years 0.01 2.20 [1.78, 2.71] 1.9e-13 166
5 years 0.02 16.90 [14.41, 19.81] <1e-100 731
1 year 0.02 91.86 [80.17, 105.27] <1e-100 1826

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: LUNG_CANCER_MESOT – Lung cancer and mesothelioma
GWS hits:

Survival analyses between endpoints

Plot

before Lung cancer and mesothelioma
after Lung cancer and mesothelioma

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Drugs most likely to be purchased after Lung cancer and mesothelioma