Non-small cell lung cancer

C3_LUNG_NONSMALL

non-small cell lung carcinoma: A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 C34.[123457]

Cause of death: ICD-10 C34.[123457]

3108

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

3108

Check minimum number of events None

3108

Include endpoints None

3108

C3_LUNG_NONSMALL

Extra metadata

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Non-small cell lung cancer based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3005	922	2083
Unadjusted prevalence (%)	0.97	0.53	1.54
Mean age at first event (years)	69.91	67.15	71.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.31	28.80 [21.26, 39.01]	<1e-100	1466
15 years	0.01	2.28 [1.71, 3.04]	2.0e-8	88
5 years	0.02	17.97 [14.80, 21.81]	<1e-100	419
1 year	0.02	91.84 [79.50, 106.10]	<1e-100	958

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_LUNG_NONSMALL – Non-small cell lung cancer
GWS hits: 1

Survival analyses between endpoints

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Plot

before Non-small cell lung cancer
after Non-small cell lung cancer

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Table

Loading survival analyses table

Drugs most likely to be purchased after Non-small cell lung cancer

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