Non-small cell lung cancer, adenocarcinoma

C3_NSCLC_ADENO

non-small cell lung carcinoma: A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

HLP_C3_NSCLC_ADENO

1130

Filter registries

Cause of death: ICD-10 C34

Cause of death: ICD-9 162

Cause of death: ICD-8 162

Cancer registry: Topography ICD-O-3 C34

Cancer registry: Morphology ICD-O-3 8140

Cancer registry: Behaviour codes 3

1130

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

1130

Check minimum number of events None

1130

Include endpoints None

1130

C3_NSCLC_ADENO

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Non-small cell lung cancer, adenocarcinoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1086	383	703
Unadjusted prevalence (%)	0.35	0.22	0.52
Mean age at first event (years)	68.86	67.42	69.64

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.36	33.99 [24.73, 46.71]	<1e-100	516
15 years	0.02	2.59 [1.78, 3.75]	6.0e-7	36
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_NSCLC_ADENO – Non-small cell lung cancer, adenocarcinoma
GWS hits: 1

Survival analyses between endpoints

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Plot

before Non-small cell lung cancer, adenocarcinoma
after Non-small cell lung cancer, adenocarcinoma

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Table

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Drugs most likely to be purchased after Non-small cell lung cancer, adenocarcinoma

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