Malignant neoplasm of respiratory system and intrathoracic organs

MESH PheWeb

C3_RESPIRATORY_INTRATHORACIC

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

C3_NASAL_CAVITY_MIDDLE_EAR

C3_ACCESSORY_SINUS

C3_LARYNX

C3_TRACHEA

C3_BRONCHUS_LUNG

C3_THYMUS

C3_HEART_MEDIASTINUM_PLEURA

C3_RESPIRATORY_INTRATHORACIC3_NAS

4847

C3_RESPIRATORY_INTRATHORACIC

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of respiratory system and intrathoracic organs based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4689	1080	3609
Unadjusted prevalence (%)	1.52	0.62	2.67
Mean age at first event (years)	69.36	65.80	70.43

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.23	18.62 [10.27, 33.78]	6.1e-22	2726
15 years	0.01	1.93 [1.21, 3.08]	5.9e-3	184
5 years	0.02	15.66 [12.64, 19.40]	<1e-100	721
1 year	0.02	96.57 [84.22, 110.74]	<1e-100	1805

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_RESPIRATORY_INTRATHORACIC – Malignant neoplasm of respiratory system and intrathoracic organs
GWS hits: 2

Survival analyses between endpoints

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Plot

before Malignant neoplasm of respiratory system and intrathoracic organs
after Malignant neoplasm of respiratory system and intrathoracic organs

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Table

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Drugs most likely to be purchased after Malignant neoplasm of respiratory system and intrathoracic organs

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