Ischemic heart diseases


coronary thrombosis: Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 I20-I25
Cause of death: ICD-10 I20-I25


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Ischemic heart diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 49030 17060 31970
Unadjusted prevalence (%) 15.89 9.83 23.68
Mean age at first event (years) 63.94 65.14 63.29


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.66 [3.37, 3.98] <1e-100 13939
15 years 0.01 2.11 [1.93, 2.30] 1.0e-65 5458
5 years 0.00 3.58 [3.30, 3.88] <1e-100 2885
1 year 0.00 26.25 [23.23, 29.67] <1e-100 3979

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_ISCHHEART – Ischemic heart diseases
GWS hits: 39

Survival analyses between endpoints


before Ischemic heart diseases
after Ischemic heart diseases

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Drugs most likely to be purchased after Ischemic heart diseases