Myocardial infarction

I9_MI

myocardial infarction: Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I21, I22

Hospital discharge: ICD-9 410

Hospital discharge: ICD-8 410

Cause of death: ICD-10 I21, I22

Cause of death: ICD-9 410

Cause of death: ICD-8 410

21098

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

21098

Check minimum number of events None

21098

Include endpoints None

21098

I9_MI

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Myocardial infarction based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	20404	5601	14803
Unadjusted prevalence (%)	6.61	3.23	10.96
Mean age at first event (years)	65.93	69.22	64.68

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.08 [3.64, 4.57]	<1e-100	7503
15 years	0.01	1.93 [1.73, 2.15]	1.2e-32	2533
5 years	0.00	3.59 [3.27, 3.95]	<1e-100	1630
1 year	0.00	27.52 [24.50, 30.90]	<1e-100	2683

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_MI – Myocardial infarction
GWS hits: 23

Survival analyses between endpoints

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Plot

before Myocardial infarction
after Myocardial infarction

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Myocardial infarction

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