Major coronary heart disease event excluding revascularizations

DOID EFO MESH PheWeb

I9_CHD_NOREV

intermediate coronary syndrome: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I20.0, I21, I22

Hospital discharge: ICD-9 410|4110

Hospital discharge: ICD-8 410|4110

Cause of death: ICD-10 I21, I22, I23, I24, I25, I46, R96, R98

Cause of death: ICD-9 41[0-4]|798

Cause of death: ICD-8 41[0-4]|798

Cause of death: excluded ICD-9 7980A

29825

Check pre-conditions, main-only, mode, ICD version

Check only main diagnosis Yes, side diagnoses are not checked

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

28309

Check minimum number of events None

28309

Include endpoints

K.I9_MI

28373

I9_CHD_NOREV

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Major coronary heart disease event excluding revascularizations based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	27443	8124	19319
Unadjusted prevalence (%)	8.89	4.68	14.31
Mean age at first event (years)	66.12	68.63	65.07

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	4.91 [4.44, 5.43]	<1e-100	10293
15 years	0.01	2.25 [2.03, 2.49]	2.3e-53	3159
5 years	0.00	3.89 [3.55, 4.26]	<1e-100	1905
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CHD_NOREV – Major coronary heart disease event excluding revascularizations
GWS hits: 22

Survival analyses between endpoints

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Plot

before Major coronary heart disease event excluding revascularizations
after Major coronary heart disease event excluding revascularizations

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Table

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Drugs most likely to be purchased after Major coronary heart disease event excluding revascularizations

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