Hard cardiovascular diseases

I9_CVD_HARD

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

48263

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I9_CVD_HARD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 46706 15726 30980
Unadjusted prevalence (%) 15.14 9.06 22.94
Mean age at first event (years) 64.93 66.32 64.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.13 [4.70, 5.59] <1e-100 14314
15 years 0.02 2.77 [2.53, 3.03] <1e-100 5194
5 years 0.00 4.67 [4.30, 5.08] <1e-100 3019
1 year 0.01 36.48 [32.23, 41.30] <1e-100 4736

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CVD_HARD – Hard cardiovascular diseases
GWS hits: 21

Survival analyses between endpoints

Plot

before Hard cardiovascular diseases
after Hard cardiovascular diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hard cardiovascular diseases