Stroke, excluding SAH


cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 I61, I63, I64
Hospital discharge: ICD-9 431|4330A|4331A|4339A|4340A|4341A|4349A|436
Hospital discharge: ICD-8 431|433|434|436
Hospital discharge: excluded ICD-10 I63.6
Hospital discharge: excluded ICD-8 43101|43191
Cause of death: ICD-10 I61, I63, I64
Cause of death: ICD-9 431|4330A|4331A|4339A|4340A|4341A|4349A|436
Cause of death: ICD-8 431|433|434|436
Cause of death: excluded ICD-10 I63.6
Cause of death: excluded ICD-8 43101|43191


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 18720 7319 11401
Unadjusted prevalence (%) 6.07 4.22 8.44
Mean age at first event (years) 66.39 66.19 66.52


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.55 [4.04, 5.12] <1e-100 6180
15 years 0.01 1.94 [1.72, 2.18] 9.1e-27 1996
5 years 0.01 4.51 [4.10, 4.96] <1e-100 1749
1 year 0.00 22.09 [19.70, 24.78] <1e-100 2014

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_STR – Stroke, excluding SAH
GWS hits: 1

Survival analyses between endpoints


before Stroke, excluding SAH
after Stroke, excluding SAH

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Stroke, excluding SAH