Status post-ami

I9_POSTAMI

heart aneurysm: A localized bulging or dilatation in the muscle wall of a heart (myocardium), usually in the left ventricle. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are hematoma caused by myocardial rupture.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I25.3
Hospital discharge: ICD-9 412
Hospital discharge: ICD-8 412
Cause of death: ICD-10 I25.3
Cause of death: ICD-9 412
Cause of death: ICD-8 412

2501

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2501

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Check minimum number of events None

2501

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Include endpoints None

2501

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I9_POSTAMI

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I25
Name in latin Aneurysma cordis

Summary Statistics

Key figures

All Female Male
Number of individuals 2429 387 2042
Unadjusted prevalence (%) 0.79 0.22 1.51
Mean age at first event (years) 55.61 56.72 55.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.82 [1.50, 2.21] 1.4e-9 1302
15 years 0.01 1.32 [1.13, 1.53] 4.1e-4 660
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_POSTAMI – Status post-ami
GWS hits: 3

Survival analyses between endpoints

Plot

before Status post-ami
after Status post-ami

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