SLE-related co-morbidities

SLE_COMORB

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

69000

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SLE_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 66847 25863 40984
Unadjusted prevalence (%) 21.67 14.90 30.35
Mean age at first event (years) 63.01 63.46 62.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.69 [4.35, 5.05] <1e-100 17112
15 years 0.01 2.89 [2.67, 3.14] <1e-100 6915
5 years 0.00 4.65 [4.28, 5.05] <1e-100 3697
1 year 0.01 28.27 [24.78, 32.25] <1e-100 4440

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: SLE_COMORB – SLE-related co-morbidities
GWS hits:

Survival analyses between endpoints

Plot

before SLE-related co-morbidities
after SLE-related co-morbidities

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Drugs most likely to be purchased after SLE-related co-morbidities