Diabetes-related co-morbidities/complications

PheWeb

DM_COMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_ISCHHEART

C_STROKE

DM_PERIPHATHERO

DM_NEPHROPATHY

DM_NEPHORAPATHY_OPER

DM_RETINOPATHY

CHARCOT

DM_NEUROPATHY

DM_PERIPH_ANGIOPATHY

DM_SEVERAL_COMPLICATIONS

DM_KETOACIDOSIS

DM_HYPOGLYC

86219

DM_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diabetes-related co-morbidities/complications based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	83557	34102	49455
Unadjusted prevalence (%)	27.08	19.65	36.63
Mean age at first event (years)	59.84	59.41	60.15

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	5.01 [4.67, 5.38]	<1e-100	18711
15 years	0.02	3.22 [2.98, 3.47]	<1e-100	8049
5 years	0.00	4.95 [4.56, 5.38]	<1e-100	4088
1 year	0.00	25.15 [21.89, 28.89]	<1e-100	4035

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_COMORB – Diabetes-related co-morbidities/complications
GWS hits:

Survival analyses between endpoints

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Plot

before Diabetes-related co-morbidities/complications
after Diabetes-related co-morbidities/complications

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Diabetes-related co-morbidities/complications

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