Charcot foot

CHARCOT

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

381

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

376

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Check minimum number of events None

376

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Include endpoints None

376

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CHARCOT

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 360 140 220
Unadjusted prevalence (%) 0.12 0.08 0.16
Mean age at first event (years) 55.43 53.32 56.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.92 [3.09, 15.50] 2.5e-6 68
15 years 0.02 3.40 [1.48, 7.82] 3.9e-3 33
5 years 0.01 8.13 [3.93, 16.85] 1.7e-8 26
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHARCOT – Charcot foot
GWS hits: 0

Survival analyses between endpoints

Plot

before Charcot foot
after Charcot foot

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