Polyarthropathies

M13_POLYARTHROPATHIES

obsolete_juvenile idiopathic arthritis: ['A group of chronic, inflammatory childhood disorders of unknown etiology that primarily involve joints.']

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M05-M14
Cause of death: ICD-10 M05-M14

22818

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

22818

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Check minimum number of events None

22818

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M13_POLYARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Polyarthropathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 24310 13314 10996
Unadjusted prevalence (%) 7.88 7.67 8.14
Mean age at first event (years) 52.52 49.33 56.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.31 [2.02, 2.66] 1.0e-32 2857
15 years 0.01 1.35 [1.19, 1.54] 6.2e-6 1211
5 years 0.00 2.78 [2.48, 3.12] 3.1e-69 800
1 year 0.00 6.28 [5.40, 7.31] <1e-100 370

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLYARTHROPATHIES – Polyarthropathies
GWS hits: 14

Survival analyses between endpoints

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Plot

before Polyarthropathies
after Polyarthropathies

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Drugs most likely to be purchased after Polyarthropathies

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