Arthropathies

DOID EFO MESH SNOMED PheWeb

M13_ARTHROPATHIES

joint disease: Any disorder of the joints.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M00-M25

Cause of death: ICD-10 M00-M25

101658

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

101658

Check minimum number of events None

101658

Include endpoints

M13_PYOGARTH

M13_REACTARTH

M13_POLYARTHROPATHIES

M13_ARTHROSIS

M13_OTHERJOINT

109835

M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Arthropathies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	106537	62812	43725
Unadjusted prevalence (%)	34.53	36.20	32.38
Mean age at first event (years)	49.83	48.73	51.41

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.13 [1.03, 1.23]	6.3e-3	8678
15 years	0.01	0.83 [0.77, 0.89]	1.4e-6	4196
5 years	0.00	1.36 [1.26, 1.47]	1.3e-14	1784
1 year	0.00	2.27 [1.99, 2.58]	6.1e-36	557

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROPATHIES – Arthropathies
GWS hits: 8

Survival analyses between endpoints

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Plot

before Arthropathies
after Arthropathies

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Table

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Drugs most likely to be purchased after Arthropathies

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