Reactive arthropathies

M13_REACTARTH

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M02, M03*

Hospital discharge: ICD-9 7111|7115|7118|713

Hospital discharge: ICD-8 71490

Cause of death: ICD-10 M02, M03*

Cause of death: ICD-9 7111|7115|7118|713

Cause of death: ICD-8 71490

4341

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2322

Check minimum number of events None

2322

Include endpoints None

2322

M13_REACTARTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Reactive arthropathies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2257	1231	1026
Unadjusted prevalence (%)	0.73	0.71	0.76
Mean age at first event (years)	43.75	42.31	45.49

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.08 [1.40, 3.08]	2.6e-4	155
15 years	0.01	1.40 [0.96, 2.03]	7.7e-2	67
5 years	0.00	3.27 [2.22, 4.81]	1.8e-9	39
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_REACTARTH – Reactive arthropathies
GWS hits: 7

Survival analyses between endpoints

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Plot

before Reactive arthropathies
after Reactive arthropathies

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Reactive arthropathies

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