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Arthrosis

DOIDEFOMESHSNOMED PheWeb

M13_ARTHROSIS

Hemarthrosis: Bleeding into the joints. It may arise from trauma or spontaneously in patients with hemophilia.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M15-M19
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M15-M19
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

56283

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

56283

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Check minimum number of events None

56283

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Include endpoints

58137

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M13_ARTHROSIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 56573 32986 23587
Unadjusted prevalence (%) 18.34 19.01 17.47
Mean age at first event (years) 58.92 58.81 59.06

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.23 [1.12, 1.36] 2.1e-5 5080
15 years 0.01 0.89 [0.81, 0.97] 7.1e-3 2604
5 years 0.00 1.42 [1.30, 1.55] 9.6e-15 1176
1 year 0.00 1.72 [1.48, 2.01] 3.7e-12 273

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROSIS – Arthrosis
GWS hits: 23

Survival analyses between endpoints

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Plot

before Arthrosis
after Arthrosis

loading spinner Loading survival analyses plot