spondyloarthropathy: A group of inflammatory rheumatic diseases associated with arthritis and enthesitis, and often involving the axial skeleton. The most common form of spondyloarthritis is ankylosing spondylitis. Other forms include axial spondyloarthritis, peripheral spondyloarthritis, reactive arthritis, psoriatic arthritis/spondylitis and enteropathic arthritis/spondylitis.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M17
Hospital discharge: ICD-9 7151F|7152F
Hospital discharge: ICD-8 71301
Cause of death: ICD-10 M17
Cause of death: ICD-9 7151F|7152F
Cause of death: ICD-8 71301


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M15-M19
Name in latin Gonarthrosis

Summary Statistics

Key figures

All Female Male
Number of individuals 34417 20358 14059
Unadjusted prevalence (%) 11.15 11.73 10.41
Mean age at first event (years) 59.07 59.18 58.91


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.08 [0.95, 1.23] 2.4e-1 3022
15 years 0.00 0.80 [0.72, 0.90] 1.5e-4 1574
5 years 0.00 1.24 [1.11, 1.39] 2.4e-4 655
1 year 0.00 1.43 [1.17, 1.74] 4.2e-4 140

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_ARTHROSIS_KNEE – Gonarthrosis
GWS hits: 20

Survival analyses between endpoints


before Gonarthrosis
after Gonarthrosis

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