Primary gonarthrosis, bilateral

MESH PheWeb

PRIM_KNEEARTHROSIS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M17.0

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M17.0

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

13241

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13241

Check minimum number of events None

13241

Include endpoints None

13241

PRIM_KNEEARTHROSIS

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M17

Name in latin Gonarthrosis primaria bilateralis

Similar endpoints

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List of similar endpoints to Primary gonarthrosis, bilateral based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12896	7973	4923
Unadjusted prevalence (%)	4.18	4.59	3.65
Mean age at first event (years)	63.85	63.56	64.30

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.34 [1.08, 1.66]	6.7e-3	1079
15 years	0.01	0.95 [0.79, 1.13]	5.4e-1	609
5 years	0.00	1.41 [1.18, 1.67]	1.0e-4	273
1 year	0.00	1.58 [1.18, 2.12]	2.1e-3	58

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: PRIM_KNEEARTHROSIS – Primary gonarthrosis, bilateral
GWS hits: 6

Survival analyses between endpoints

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Plot

before Primary gonarthrosis, bilateral
after Primary gonarthrosis, bilateral

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Table

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Drugs most likely to be purchased after Primary gonarthrosis, bilateral

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