Gonarthrosis [arthrosis of knee](FG)

MESH PheWeb

KNEE_ARTHROSIS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

PRIM_KNEEARTHROSIS

SCND_OTH_KNEEARTHROSIS

M13_ARTHROSIS_KNEE

35334

KNEE_ARTHROSIS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Gonarthrosis [arthrosis of knee](FG) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	34417	20358	14059
Unadjusted prevalence (%)	11.15	11.73	10.41
Mean age at first event (years)	59.07	59.18	58.91

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.15 [1.02, 1.30]	1.9e-2	3022
15 years	0.01	0.85 [0.76, 0.94]	2.1e-3	1574
5 years	0.00	1.28 [1.15, 1.43]	1.2e-5	655
1 year	0.00	1.46 [1.20, 1.78]	1.3e-4	140

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KNEE_ARTHROSIS – Gonarthrosis [arthrosis of knee](FG)
GWS hits: 19

Survival analyses between endpoints

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Plot

before Gonarthrosis [arthrosis of knee](FG)
after Gonarthrosis [arthrosis of knee](FG)

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Table

Loading survival analyses table

Drugs most likely to be purchased after Gonarthrosis [arthrosis of knee](FG)

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