Ohter specific/unspecified arthritis

M13_ARTHRITISNAS

arthritis: An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M13.8, M13.9
Hospital discharge: ICD-9 7169
Hospital discharge: ICD-8 7110[8-9]|71498
Cause of death: ICD-10 M13.8, M13.9
Cause of death: ICD-9 7169
Cause of death: ICD-8 7110[8-9]|71498

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

7195

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M13_ARTHRITISNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 6979 4274 2705
Unadjusted prevalence (%) 2.26 2.46 2.00
Mean age at first event (years) 51.44 49.20 55.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.00 [2.35, 3.83] 1.5e-18 437
15 years 0.01 1.52 [1.18, 1.95] 1.2e-3 188
5 years 0.00 2.93 [2.20, 3.90] 1.6e-13 152
1 year 0.00 5.19 [3.64, 7.39] 6.3e-20 53

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_ARTHRITISNAS – Ohter specific/unspecified arthritis
GWS hits: 0

Survival analyses between endpoints

Plot

before Ohter specific/unspecified arthritis
after Ohter specific/unspecified arthritis

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Drugs most likely to be purchased after Ohter specific/unspecified arthritis