Kaschin-Beck disease

M13_KASHINBECK

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 M12.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M12.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

16

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

16

diagram downward connector

Check minimum number of events None

16

diagram downward connector

Include endpoints None

16

diagram downward connector
M13_KASHINBECK

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M12
Name in latin Morbus Kashin-Beck

Summary Statistics

Key figures

All Female Male
Number of individuals 15 9 6
Unadjusted prevalence (%) 0.00 0.01 0.00
Mean age at first event (years) 59.66 57.82 62.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_KASHINBECK – Kaschin-Beck disease
GWS hits:

Survival analyses between endpoints

Plot

before Kaschin-Beck disease
after Kaschin-Beck disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Kaschin-Beck disease