Diabetic hypoglycemia

DM_HYPOGLYC

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E10.00, E11.00, E16.0#, E16.2

Hospital discharge: ICD-9 2510B|2512

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E10.00, E11.00, E16.0#, E16.2

Cause of death: ICD-9 2510B|2512

Cause of death: ICD-8 $!$

6091

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6091

Check minimum number of events None

6091

Include endpoints None

6091

DM_HYPOGLYC

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diabetic hypoglycemia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5914	2473	3441
Unadjusted prevalence (%)	1.92	1.43	2.55
Mean age at first event (years)	53.83	51.13	55.77

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.29 [4.89, 8.10]	2.5e-46	1700
15 years	0.02	2.92 [2.35, 3.64]	6.4e-22	659
5 years	0.01	5.89 [4.94, 7.03]	6.4e-86	605
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_HYPOGLYC – Diabetic hypoglycemia
GWS hits: 10

Survival analyses between endpoints

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Plot

before Diabetic hypoglycemia
after Diabetic hypoglycemia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Diabetic hypoglycemia

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